Drug‐delivering nerve conduit improves regeneration in a critical‐sized gap
نویسندگان
چکیده
منابع مشابه
Prostaglandin E1 Combined with Chitosan Conduit Improves Sciatic Nerve Regeneration in Rats
Objective- To studylocal effect of prostaglandin E1on sciatic nerve regeneration Design- Experimental study Animals- Sixty male healthy white Wistar rats Procedures- Sixty animals were divided into four experimental groups (n = 15), randomly: Trasnsected (TC), Sham-operation (SHAM), control (CHIT) and prostagl...
متن کاملProstaglandin E1 Combined with Chitosan Conduit Improves Sciatic Nerve Regeneration in Rats
ObjectiveTo study local effect of prostaglandin E1on sciatic nerve regeneration DesignExperimental study AnimalsSixty male healthy white Wistar rats ProceduresSixty animals were divided into four experimental groups (n = 15), randomly: Trasnsected (TC), Sham-operation (SHAM), control (CHIT) and prostaglandin E1treated (CHIT/PGE) groups. In SHAM group after anesthesia left sciatic nerve was expo...
متن کاملAlpha-lipoic acid loaded in chitosan conduit enhances sciatic nerve regeneration in rat
Objective(s): To investigate the effect of topical administration of alpha-lipoic acid into chitosan conduit on peripheral nerve regeneration using a rat sciatic nerve transection model. Materials and Methods: Forty five Wistar rats were divided into three experimental groups randomly. A 10-mm gap of sciatic nerve was bridged with a chitosan conduit following surgical preparation and anesthesia...
متن کاملUse of Chitosan Conduit for Bridging Small-Gap Peripheral Nerve Defect in Sciatic Nerve Transection Model of Rat
Objective-To evaluate effect of chitosan conduit for peripheral nerve regeneration using sciatic nerve transection model in rat Design- Experimental in vivo study. Animals- Sixty healthy male Wistar rats. Procedures-The rats were divided into four experimental groups (n=15) randomly. In sham group the left sciatic nerve was exposed through a gluteal muscle incision and after careful...
متن کاملLow-Level Laser-Accelerated Peripheral Nerve Regeneration within a Reinforced Nerve Conduit across a Large Gap of the Transected Sciatic Nerve in Rats
This study proposed a novel combination of neural regeneration techniques for the repair of damaged peripheral nerves. A biodegradable nerve conduit containing genipin-cross-linked gelatin was annexed using beta-tricalcium phosphate (TCP) ceramic particles (genipin-gelatin-TCP, GGT) to bridge the transection of a 15 mm sciatic nerve in rats. Two trigger points were irradiated transcutaneously u...
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ژورنال
عنوان ژورنال: Biotechnology and Bioengineering
سال: 2018
ISSN: 0006-3592,1097-0290
DOI: 10.1002/bit.26837